Urinary Cytology & FISH
Below you find the correct answers to the 52 cases of the quiz.
The online quiz has been answered by 246 specialists around the world in April 2005.


Case 1
Bladder wash. 86 year-old woman.

(Click on the small thumbnail images to see the full view! Close the image window after viewing the image!)
What is your diagnosis for case 1? (required)
FISH positive
Biopsy: Noninvasive high grade papillary urothelial carcinoma pTa G2>G3
 1 Negative, benign — 2.4%
 2 Reactive changes — 16.3%
 3 Mild atypia, cannot exclude low grade neoplasia — 13.4%
 4 Moderate atypia, suspicious — 35.0%
 5 Severe atypia, positive — 32.9%

Case 2
Voided urine. 52 year-old man.

What is your diagnosis for case 2 (required)
FISH negative
Several normal follow up cytologies
 1 Negative, benign — 0.8%
 2 Reactive changes — 41.1%
 3 Mild atypia, cannot exclude low grade neoplasia — 22.4%
 4 Moderate atypia, suspicious — 25.2%
 5 Severe atypia, positive — 10.6%

Case 3
Bladder wash. Follow-up cystoscopy for recurrent carcinoma in situ and high-grade papillary urothelial tumor (pTa G3).
65 year-old woman.

What is your diagnosis for case 3 (required)
FISH positive
Biopsy: Carcinoma in situ
 1 Negative, benign — 0.0%
 2 Reactive changes — 4.1%
 3 Mild atypia, cannot exclude low grade neoplasia — 2.4%
 4 Moderate atypia, suspicious — 22.0%
 5 Severe atypia, positive — 71.5%

Case 4
Bladder wash. Follow-up cystoscopy for recurrent high-grade papillary urothelial tumors (pTa G3 and pT1 G3) and carcinoma in situ.
80 year-old man.

What is your diagnosis for case 4 (required)
FISH positive
Biopsy: Carcinoma in situ and invasive high grade papillary urothelial carcinoma pT1
 1 Negative, benign — 0.0%
 2 Reactive changes — 2.0%
 3 Mild atypia, cannot exclude low grade neoplasia — 0.8%
 4 Moderate atypia, suspicious — 4.1%
 5 Severe atypia, positive — 93.1%

Case 5
Bladder wash. Follow-up cystoscopy after treatment for low-grade papillary urothelial tumor (pTa G2).
58 year-old man.

What is your diagnosis for case 5 (required)
FISH positive del 9p21
Biopsy: Papillary urothelial neoplasm of low malignant potential (PUNLMP) pTa
 1 Negative, benign — 15.0%
 2 Reactive changes — 33.3%
 3 Mild atypia, cannot exclude low grade neoplasia — 39.8%
 4 Moderate atypia, suspicious — 9.8%
 5 Severe atypia, positive — 2.0%

Case 6
Bladder wash. Follow-up cystoscopy after treatment for high-grade papillary urothelial tumor (pT1 G3).
80 year-old man.

What is your diagnosis for case 6 (required)
FISH positive
Biopsy: Invasive high grade papillary urothelial carcinoma pT1 G2>G3
 1 Negative, benign — 4.5%
 2 Reactive changes — 48.4%
 3 Mild atypia, cannot exclude low grade neoplasia — 20.3%
 4 Moderate atypia, suspicious — 19.9%
 5 Severe atypia, positive — 6.9%

Case 7
Bladder wash. Follow-up cystoscopy after treatment for papillary neoplasm of low malignant potential (pTa G1).
73 year-old man.

What is your diagnosis for case 7 (required)
FISH positive
Biopsy: Noninvasive low grade papillary urothelial carcinoma pTa
 1 Negative, benign — 8.9%
 2 Reactive changes — 35.0%
 3 Mild atypia, cannot exclude low grade neoplasia — 43.1%
 4 Moderate atypia, suspicious — 11.4%
 5 Severe atypia, positiv — 1.6%

Case 8
Bladder wash. 51 year-old man.

What is your diagnosis for case 8 (required)
FISH negative
Biopsy: Cystitis cystica
 1 Negative, benign — 8.5%
 2 Reactive changes — 14.6%
 3 Mild atypia, cannot exclude low grade neoplasia — 32.1%
 4 Moderate atypia, suspicious — 36.2%
 5 Severe atypia, positive — 8.5%

Case 9
Bladder wash. Diffuse redness of the bladder mucosa and papillomatous lesion. 71 year-old man.

What is your diagnosis for case 9 (required)
FISH positive
Biopsy: High grade solid transitional cell carcinoma pT1 and carcinoma in situ
 1 Negative, benign — 0.0%
 2 Reactive changes — 7.3%
 3 Mild atypia, cannot exclude low grade neoplasia — 6.1%
 4 Moderate atypia, suspicious — 31.7%
 5 Severe atypia, positive — 54.9%

Case 10
Ureteral wash. History of phenacetin (analgesic) abuse and family history of cancer of the renal pelvis. 73 year-old woman.

What is your diagnosis for case 10 (required)
FISH negative
Uneventful follow up
 1 Negative, benign — 7.3%
 2 Reactive changes — 33.3%
 3 Mild atypia, cannot exclude low grade neoplasia — 25.6%
 4 Moderate atypia, suspicious — 19.5%
 5 Severe atypia, positive — 14.2%

Case 11
Bladder wash. Follow-up cystoscopy after treatment for carcinoma in situ and high-grade papillary urothelial tumor (pT1b G3).
58 year-old man.

What is your diagnosis for case 11 (required)
FISH positive
Biopsy: Moderate dysplasia
 1 Negative, benign — 0.0%
 2 Reactive changes — 17.1%
 3 Mild atypia, cannot exclude low grade neoplasia — 10.6%
 4 Moderate atypia, suspicious — 36.2%
 5 Severe atypia, positive — 36.2%

Case 12
Bladder wash. Follow-up cystoscopy for recurrent low-grade and high-grade papillary urothelial tumors (pT1 G3 and pTa G2).
76 year-old man.

What is your diagnosis for case 12 (required)
FISH positive
Biopsy: Noninvasive low grade papillary urothelial carcinoma pTa
 1 Negative, benign — 1.6%
 2 Reactive changes — 8.5%
 3 Mild atypia, cannot exclude low grade neoplasia — 16.3%
 4 Moderate atypia, suspicious — 40.7%
 5 Severe atypia, positive — 32.9%

Case 13
Bladder wash. Follow-up cystoscopy after treatment for high-grade papillary urothelial tumor (pT1 G3) and carcinoma in situ.
BCG instillations 37, 25, and 8 months ago. 68 year-old man.

What is your diagnosis for case 13 (required)
FISH negative
Normal cystoscopy
 1 Negative, benign — 12.6%
 2 Reactive changes — 30.5%
 3 Mild atypia, cannot exclude low grade neoplasia — 21.1%
 4 Moderate atypia, suspicious — 22.8%
 5 Severe atypia, positive — 13.0%

Case 14
Ureteral wash. Right ureter and renal pelvis with thickened wall. 74 year-old woman.

What is your diagnosis for case 14 (required)
FISH negative
Retrograde pyelography: No demonstration of a tumor
 1 Negative, benign — 31.7%
 2 Reactive changes — 36.2%
 3 Mild atypia, cannot exclude low grade neoplasia — 22.0%
 4 Moderate atypia, suspicious — 7.7%
 5 Severe atypia, positive — 2.4%

Case 15
Bladder wash. Follow-up cystoscopy after treatment for low-grade papillary urothelial tumor (pTa G1).
77 year-old woman.

What is your diagnosis for case 15 (required)
FISH negative, tetraploid umbrella cells
Bladder wash with reactive changes 8 months later
 1 Negative, benign — 11.4%
 2 Reactive changes — 46.7%
 3 Mild atypia, cannot exclude low grade neoplasia — 35.8%
 4 Moderate atypia, suspicious — 4.9%
 5 Severe atypia, positive — 1.2%

Case 16
Bladder wash. 61 year-old man.

What is your diagnosis for case 16 (required)
FISH negative
Biopsy: Papillary hyperplasia and chronic cystitis
 1 Negative, benign — 30.1%
 2 Reactive changes — 36.6%
 3 Mild atypia, cannot exclude low grade neoplasia — 26.8%
 4 Moderate atypia, suspicious — 5.7%
 5 Severe atypia, positive — 0.8%

Case 17
Bladder wash. History of hematuria. 58 year-old man.

What is your diagnosis for case 17 (required)
FISH negative
Normal cystoscopy
 1 Negative, benign — 3.3%
 2 Reactive changes — 17.1%
 3 Mild atypia, cannot exclude low grade neoplasia — 30.9%
 4 Moderate atypia, suspicious — 37.8%
 5 Severe atypia, positive — 11.0%

Case 18
Bladder wash. Follow-up cystoscopy after treatment for high-grade papillary urothelial tumor (pTa G2-3).
67 year-old woman.

What is your diagnosis for case 18 (required)
FISH positive
Biopsy: Noninvasive high grade papillary urothelial carcinoma pTa
 1 Negative, benign — 0.0%
 2 Reactive changes — 2.0%
 3 Mild atypia, cannot exclude low grade neoplasia — 0.8%
 4 Moderate atypia, suspicious — 13.8%
 5 Severe atypia, positive — 83.3%

Case 19
Bladder wash. Follow-up cystoscopy after treatment for low-grade papillary urothelial tumor (pTa G1-2).
48 year-old woman.

What is your diagnosis for case 19 (required)
FISH positive del 9p21
Biopsy: Noninvasive low grade papillary urothelial carcinoma pTa
 1 Negative, benign — 7.3%
 2 Reactive changes — 45.5%
 3 Mild atypia, cannot exclude low grade neoplasia — 28.0%
 4 Moderate atypia, suspicious — 16.3%
 5 Severe atypia, positive — 2.8%

Case 20
Bladder wash. Episodes of recurrent macrohematuria. 72 year-old man.
What is your diagnosis for case 20 (required)
FISH negative
Biopsy: Inconspicious mucosa
 1 Negative, benign — 8.9%
 2 Reactive changes — 26.8%
 3 Mild atypia, cannot exclude low grade neoplasia — 43.5%
 4 Moderate atypia, suspicious — 17.9%
 5 Severe atypia, positive — 2.8%

Case 21
Renal pelvic wash. History of macrohematuria. 57 year-old woman.

What is your diagnosis for case 21 (required)
FISH negative, few tetraploid cells
Urolithiasis at follow up
 1 Negative, benign — 10.6%
 2 Reactive changes — 22.8%
 3 Mild atypia, cannot exclude low grade neoplasia — 43.5%
 4 Moderate atypia, suspicious — 13.4%
 5 Severe atypia, positive — 9.8%

Case 22
Bladder wash. Recurrent microhematuria for years. Chemotherapy for breast cancer. 63 year-old woman.

What is your diagnosis for case 22 (required)
FISH negative
Uneventful follow up
 1 Negative, benign — 21.5%
 2 Reactive changes — 45.9%
 3 Mild atypia, cannot exclude low grade neoplasia — 22.4%
 4 Moderate atypia, suspicious — 8.5%
 5 Severe atypia, positive — 1.6%

Case 23
Bladder wash. 85 year-old man.

What is your diagnosis for case 23 (required)
Both cytology and biopsy FISH negative!
Biopsy: Noninvasive low grade papillary urothelial carcinoma pTa
 1 Negative, benign — 9.8%
 2 Reactive changes — 35.0%
 3 Mild atypia, cannot exclude low grade neoplasia — 29.7%
 4 Moderate atypia, suspicious — 19.9%
 5 Severe atypia, positive — 5.7%

Case 24
Renal pelvic wash. Recurrent cystitis and moderate celllular atypia in a previous bladder wash. 39 year-old woman.

What is your diagnosis for case 24 (required)
FISH negative
Biopsy: Chronic cystitis. Normal bladder wash 3 months later
 1 Negative, benign — 15.9%
 2 Reactive changes — 47.6%
 3 Mild atypia, cannot exclude low grade neoplasia — 25.6%
 4 Moderate atypia, suspicious — 9.8%
 5 Severe atypia, positive — 1.2%

Case 25
Bladder wash. 66 year-old man.

What is your diagnosis for case 25 (required)
FISH negative
Biopsy: Cystitis cystica et glandularis
 1 Negative, benign — 10.2%
 2 Reactive changes — 32.5%
 3 Mild atypia, cannot exclude low grade neoplasia — 33.7%
 4 Moderate atypia, suspicious — 17.5%
 5 Severe atypia, positive — 6.1%

Case 26
Bladder wash. Macrohematuria. 82 year-old woman.

What is your diagnosis for case 26 (required)
FISH negative
Biopsy: Cystitis with reactive atypia
 1 Negative, benign — 10.2%
 2 Reactive changes — 43.5%
 3 Mild atypia, cannot exclude low grade neoplasia — 24.0%
 4 Moderate atypia, suspicious — 19.5%
 5 Severe atypia, positive — 2.8%

Case 27
Voided urine. Analgesic nephropathy. Follow-up after treatment for recurrent papillary neoplasms
of low malignant potential (pTa G1). 63 year-old man.

What is your diagnosis for case 27 (required)
FISH negative, few tetraploid cells
Decoy cells. Biopsy: Polyoma virus nephropathy. See the corresponding virtual slide of this biopsy
 1 Negative, benign — 4.5%
 2 Reactive changes — 38.2%
 3 Mild atypia, cannot exclude low grade neoplasia — 11.4%
 4 Moderate atypia, suspicious — 24.0%
 5 Severe atypia, positive — 22.0%

Case 28
Bladder wash. Bladder diverticulum. Prostatic hyperplasia. 63 year-old man.

What is your diagnosis for case 28 (required)
FISH negative
Uneventful follow up
 1 Negative, benign — 4.5%
 2 Reactive changes — 35.8%
 3 Mild atypia, cannot exclude low grade neoplasia — 27.2%
 4 Moderate atypia, suspicious — 21.1%
 5 Severe atypia, positive — 11.4%

Case 29
Renal pelvic wash. Follow-up after treatment for recurrent low grade papillary urothelial tumors (2x pTa, G1; 1x pTa, G2). 55 year-old man.

What is your diagnosis for case 29 (required)
FISH negative
Biopsy: Granulation tissue polyp. Inconspicious washing cytology of the pyelon
 1 Negative, benign — 19.9%
 2 Reactive changes — 28.9%
 3 Mild atypia, cannot exclude low grade neoplasia — 39.0%
 4 Moderate atypia, suspicious — 9.8%
 5 Severe atypia, positive — 2.4%

Case 30
Bladder wash. Microhematuria and voiding difficulties. 67 year-old woman.

What is your diagnosis for case 30 (required)
FISH negative
Uneventful follow up
 1 Negative, benign — 18.7%
 2 Reactive changes — 32.1%
 3 Mild atypia, cannot exclude low grade neoplasia — 32.9%
 4 Moderate atypia, suspicious — 14.2%
 5 Severe atypia, positive — 2.0%

Case 31
Voided urine. 75 year-old man.

What is your diagnosis for case 31 (required)
FISH negative, few tetraploid cells
Uneventful follow up
 1 Negative, benign — 4.5%
 2 Reactive changes — 20.3%
 3 Mild atypia, cannot exclude low grade neoplasia — 21.5%
 4 Moderate atypia, suspicious — 39.4%
 5 Severe atypia, positive — 14.2%

Case 32
Bladder wash. Nephroureterectomy for the treatment of multiple papillary urothelial tumors (pTa G2-3) one year ago.
Follow-up cystoscopy. 59 year-old man.

What is your diagnosis for case 32 (required)
FISH positive del 9p21
Biopsy: Noninvasive low grade papillary urothelial carcinoma pTa
 1 Negative, benign — 6.9%
 2 Reactive changes — 15.0%
 3 Mild atypia, cannot exclude low grade neoplasia — 29.7%
 4 Moderate atypia, suspicious — 33.3%
 5 Severe atypia, positive — 15.0%

Case 33
Voided urine. 63 year-old man.

What is your diagnosis for case 33 (required)
FISH negative
Decoy cells. Biopsy: Polyoma nephropathy
 1 Negative, benign — 6.5%
 2 Reactive changes — 37.0%
 3 Mild atypia, cannot exclude low grade neoplasia — 2.0%
 4 Moderate atypia, suspicious — 6.9%
 5 Severe atypia, positive — 47.6%

Case 34
Bladder wash. Diabetic nephropathy. Benign prostatic hyperplasia. 61 year-old man.

What is your diagnosis for case 34 (required)
FISH negative
Cystoscopy: No tumor
 1 Negative, benign — 13.4%
 2 Reactive changes — 52.4%
 3 Mild atypia, cannot exclude low grade neoplasia — 20.3%
 4 Moderate atypia, suspicious — 12.2%
 5 Severe atypia, positive — 1.6%

Case 35
Voided urine. History of macrohematuria. 50 year-old man.

What is your diagnosis for case 35 (required)
FISH negative
Uneventful follow up
 1 Negative, benign — 35.0%
 2 Reactive changes — 34.6%
 3 Mild atypia, cannot exclude low grade neoplasia — 21.1%
 4 Moderate atypia, suspicious — 8.1%
 5 Severe atypia, positive — 1.2%

Case 36
Bladder wash. Follow-up cystoscopy after treatment for recurrent low-grade papillary urothelial tumors (pTa G1 and pTa G2).
72 year-old man.

What is your diagnosis for case 36 (required)
Cytology FISH negative!
Biopsy: Papillary urothelial neoplasm of low malignant potential (PUNLMP) pTa
 1 Negative, benign — 21.1%
 2 Reactive changes — 33.3%
 3 Mild atypia, cannot exclude low grade neoplasia — 36.6%
 4 Moderate atypia, suspicious — 8.1%
 5 Severe atypia, positive — 0.8%

Case 37
Bladder wash. Irregular mucosa. 75 year-old woman.

What is your diagnosis for case 37 (required)
FISH negative
Biopsy: Chronic cystitis
 1 Negative, benign — 4.1%
 2 Reactive changes — 60.6%
 3 Mild atypia, cannot exclude low grade neoplasia — 12.6%
 4 Moderate atypia, suspicious — 15.4%
 5 Severe atypia, positive — 7.3%

Case 38
Bladder wash. Tumor of the left renal pelvis. 41 year-old woman.

What is your diagnosis for case 38 (required)
FISH negative
Retrograde pyelography: Benign stenosis of ureteropelvic junction, no ureteral tumor
 1 Negative, benign — 1.2%
 2 Reactive changes — 17.5%
 3 Mild atypia, cannot exclude low grade neoplasia — 23.2%
 4 Moderate atypia, suspicious — 38.6%
 5 Severe atypia, positive — 19.5%

Case 39
Bladder wash. Hematuria. 71 year-old man.

What is your diagnosis for case 39 (required)
FISH negative
Uneventful follow up
 1 Negative, benign — 2.0%
 2 Reactive changes — 40.2%
 3 Mild atypia, cannot exclude low grade neoplasia — 14.6%
 4 Moderate atypia, suspicious — 31.7%
 5 Severe atypia, positive — 11.4%

Case 40
Bladder wash. Follow-up cystoscopy after treatment for high grade papillary urothelial carcinoma (pT1 G3).
BCG treatment 10 months ago. 81 year-old woman.

What is your diagnosis for case 40 (required)
FISH positive del 9p21
Biopsy: Invasive high grade papillary urothelial carcinoma pT2
 1 Negative, benign — 2.0%
 2 Reactive changes — 40.2%
 3 Mild atypia, cannot exclude low grade neoplasia — 14.6%
 4 Moderate atypia, suspicious — 31.7%
 5 Severe atypia, positive — 11.4%

Case 41
Bladder wash. Chronic microhematuria. 55 year-old woman.

What is your diagnosis for case 41 (required)
FISH negative
Basal cells. Uneventful follow up
 1 Negative, benign — 8.9%
 2 Reactive changes — 11.8%
 3 Mild atypia, cannot exclude low grade neoplasia — 26.0%
 4 Moderate atypia, suspicious — 25.6%
 5 Severe atypia, positive — 27.6%

Case 42
Bladder wash. Persistent microhematuria. 46 year-old man.

What is your diagnosis for case 42 (required)
FISH negative, tetraploid cells
Cystoscopy: No tumor
 1 Negative, benign — 4.9%
 2 Reactive changes — 25.6%
 3 Mild atypia, cannot exclude low grade neoplasia — 37.4%
 4 Moderate atypia, suspicious — 24.0%
 5 Severe atypia, positive — 8.1%

Case 43
Bladder wash. Breast and ovarian cancer. 46 year-old woman.

What is your diagnosis for case 43 (required)
FISH negative, few polyploid cells
Cystoscopy: No tumor
 1 Negative, benign — 5.3%
 2 Reactive changes — 36.6%
 3 Mild atypia, cannot exclude low grade neoplasia — 8.1%
 4 Moderate atypia, suspicious — 17.9%
 5 Severe atypia, positive — 32.1%

Case 44
Bladder wash. Five weeks after initiation of BCG treatment for carcinoma in situ of the bladder.
63 year-old man.

What is your diagnosis for case 44 (required)
FISH positive
Biopsy: Carcinoma in situ
 1 Negative, benign — 0.0%
 2 Reactive changes — 7.7%
 3 Mild atypia, cannot exclude low grade neoplasia — 1.2%
 4 Moderate atypia, suspicious — 13.8%
 5 Severe atypia, positive — 77.2%

Case 45
Bladder wash. Follow-up cystoscopy 9 months after treatment for carcinoma in situ of the bladder with BCG instillations.
67 year-old man.

What is your diagnosis for case 45 (required)
FISH negative
Follow up urinary cytology without atypia
 1 Negative, benign — 2.8%
 2 Reactive changes — 44.7%
 3 Mild atypia, cannot exclude low grade neoplasia — 21.1%
 4 Moderate atypia, suspicious — 24.4%
 5 Severe atypia, positive — 6.9%

Case 46
Voided urine. 22 year-old woman.

What is your diagnosis for case 46? (required)
FISH negative
Several follow up cytologies without atypia
 1 Negative, benign — 0.0%
 2 Reactive changes — 22.4%
 3 Mild atypia, cannot exclude low grade neoplasia — 8.1%
 4 Moderate atypia, suspicious — 27.2%
 5 Severe atypia, positive — 42.3%

Case 47
Bladder wash. Follow-up cystoscopy after treatment for recurrent papillary neoplasms of low malignant potential (pTa G1).
72 year-old man.

What is your diagnosis for case 47? (required)
FISH positive
Noninvasive low grade papillary urothelial carcinoma pTa
 1 Negative, benign — 1.2%
 2 Reactive changes — 16.3%
 3 Mild atypia, cannot exclude low grade neoplasia — 45.9%
 4 Moderate atypia, suspicious — 29.3%
 5 Severe atypia, positive — 7.3%

Case 48
Renal pelvic wash. Follow-up after treatment for papillary neoplasm of low malignant potential (pTa G1).
88 year-old man.

What is your diagnosis for case 48? (required)
FISH negative
Cystoscopy and retrograde pyelography: no tumor
 1 Negative, benign — 9.3%
 2 Reactive changes — 27.2%
 3 Mild atypia, cannot exclude low grade neoplasia — 36.6%
 4 Moderate atypia, suspicious — 21.5%
 5 Severe atypia, positive — 5.3%

Case 49
Bladder wash. Follow-up cystoscopy after treatment for low grade papillary urothelial tumor (pTa G2).
48 year-old woman.

What is your diagnosis for case 49? (required)
FISH positive del 9p21
Biopsy: Invasive low grade papillary urothelial carcinoma pT1
 1 Negative, benign — 11.0%
 2 Reactive changes — 26.4%
 3 Mild atypia, cannot exclude low grade neoplasia — 43.1%
 4 Moderate atypia, suspicious — 16.3%
 5 Severe atypia, positive — 3.3%

Case 50
Bladder wash. Follow-up cystoscopy after treatment for papillary neoplasm of low malignant potential (pTa G1).
74 year-old man.

What is your diagnosis for case 50? (required)
Both cytology and biopsy FISH negative!
Biopsy: Noninvasive low grade papillary urothelial carcinoma pTa
 1 Negative, benign — 17.1%
 2 Reactive changes — 46.3%
 3 Mild atypia, cannot exclude low grade neoplasia — 26.8%
 4 Moderate atypia, suspicious — 8.5%
 5 Severe atypia, positive — 1.2%

Case 51
Bladder wash. Tetraplegic patient with indwelling catheter. Sonographic detection of papillary structures in the trigonum.
41 year-old woman.

What is your diagnosis for case 51? (required)
FISH negative
Biopsy: Cystitis follicularis
 1 Negative, benign — 27.2%
 2 Reactive changes — 51.2%
 3 Mild atypia, cannot exclude low grade neoplasia — 17.9%
 4 Moderate atypia, suspicious — 3.3%
 5 Severe atypia, positive — 0.4%

Case 52
Bladder wash. Chronic hematuria. 73 year-old patient.

What is your diagnosis for case 52? (required)
FISH negative
Cells resembling decoy cells were immunocytochemically negative for SV40. Uneventful follow up
 1 Negative, benign — 0.8%
 2 Reactive changes — 15.0%
 3 Mild atypia, cannot exclude low grade neoplasia — 21.1%
 4 Moderate atypia, suspicious — 36.6%
 5 Severe atypia, positive — 26.4%
Thank you for participating!


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